It's normal to have questions during your child's treatment. Learning more can help you feel prepared. It can also help you talk with your child's healthcare team about what happens next.
This section answers common questions about steroid-refractory acute GvHD. You'll also learn what's possible with RYONCIL.
What is acute GvHD?
Acute GvHD is a serious condition that can happen after a bone marrow transplant. When a person’s unhealthy blood-forming cells (stem cells) are replaced with healthy cells from a donor, the new cells may get confused. They may attack the body of the person who got them.
What are the 2 types of GvHD?
What are the symptoms of acute GvHD?
How is acute GvHD treated?
How common is acute GvHD?
What is steroid-refractory acute GvHD?
What steroid-refractory acute GvHD treatments are available for children 2 months of age and older?
What is RYONCIL?
What is RYONCIL made of?
Is RYONCIL a steroid?
What makes RYONCIL different from other treatments for steroid-refractory acute GvHD?
How does RYONCIL work?
How well does RYONCIL work?
Does RYONCIL work in very sick children?
How was RYONCIL studied?
Who were the children included in the clinical study of RYONCIL for steroid-refractory acute GvHD?
What do we know about the children who were in the RYONCIL clinical study?
Is RYONCIL safe?
What are the most common side effects that may be associated with RYONCIL?
Were any side effects serious?
Are there any other side effects to know about?
How long will my child need to be treated with RYONCIL?
How long does treatment with RYONCIL take?
What happens before, during, and after each infusion of RYONCIL?
Do we have to get RYONCIL treatment at a transplant center?
What kind of support is available for families interested in RYONCIL?
Is RYONCIL covered by insurance?
What options are in place to help families afford treatment with RYONCIL?
See why recovery is possible with RYONCIL
Learn more about the first and only FDA-approved treatment approved just for children with steroid-refractory acute GvHD.
About RYONCIL
Get support at every step
Learning that your child has steroid-refractory acute GvHD can feel scary. But it’s important to know that you are not alone. Support is available to help your family move forward.
Get support resources
RYONCIL is a prescription medicine used to treat a condition called steroid-refractory acute graft versus host disease (SR-aGvHD) in children 2 months and older.
Do not receive Ryoncil if you are allergic to DMSO or porcine and bovine proteins (e.g., pigs or cows).
Ryoncil is not recommended if you are pregnant. Talk to your doctor about the risks and benefits of breastfeeding during Ryoncil treatment.
The most common side effects include infections, fever, bleeding, swelling, stomach pain, high blood pressure, vomiting, irregular heartbeat, diarrhea, rash, joint pain, low blood pressure, cough, and trouble breathing.
Tell your doctor about all your medical conditions, allergies, and if you are pregnant or breastfeeding.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1–800-FDA-1088.
For additional information, see full Prescribing Information.
RYONCIL is a prescription medicine used to treat a condition called steroid-refractory acute graft versus host disease (SR-aGvHD) in children 2 months and older.
Do not receive Ryoncil if you are allergic to DMSO or porcine and bovine proteins (e.g., pigs or cows).
Ryoncil is not recommended if you are pregnant. Talk to your doctor about the risks and benefits of breastfeeding during Ryoncil treatment.
The most common side effects include infections, fever, bleeding, swelling, stomach pain, high blood pressure, vomiting, irregular heartbeat, diarrhea, rash, joint pain, low blood pressure, cough, and trouble breathing.
Tell your doctor about all your medical conditions, allergies, and if you are pregnant or breastfeeding.
You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www.fda.gov/medwatch, or call 1–800-FDA-1088.
For additional information, see full Prescribing Information.
